Evaluating the Utility of Existing Animal Models in Predicting Cytokineassociated Safety Signals with Novel & Targeted Therapies
Time: 1:30 pm
day: Conference Day Two
Details:
Discussing the importance of animal models in understanding the pharmacology and toxicology of cytokines, emphasizing the need for models that accurately reflect cytokine-mediated responses
Reviewing the successes of approved therapeutics that overcame cytokine challenges in the translational stage
Using quantitative systems pharmacology models driven by cytokine data to characterize relationships between efficacy and safety in early drug development
