Immune Humanized Platforms for Preclinical Evaluation of Tumor Efficacy & Cytokine Release Mediated Toxicity
Time: 12:00 pm
Details:
• Human PBMC engraftment in MHC deficient recipients diminishes acute GvHD
• Accurate modeling of treatment induced human cytokine release in vivo
• Human donor specific differences in efficacy & toxicity for drug candidate selection