Pre-Conference Workshop Day Tuesday, May 21, 2024
Workshop A 9am-12pm
9:00 am Uncovering Novel Tools for Target Identification & Tissue Targeting Approaches for Cytokine Therapies
Synopsis
Revealing strategies for novel target discovery and selection through current approaches. Hear about the latest technologies and methodologies used to identify immune receptors and outline mechanisms of action. Join this workshop to:
- Explore how to use algorithmic models to vet out molecules • Discover high throughput approaches, AI and computational approaches for target identification
- Learn about directed evolution approaches for molecule selection • Discuss how to target the right tissue type and cell types
- Uncover collagen binding domains derived from von Willebrand factor A3 domain to increase safety and anti-tumor efficacy
Workshop B 1.00pm-4pm
1:00 pm Ensuring Translational Success by Futureproofing Your Program: Preclinical Model Selection & Predictive Biomarker Screening
Synopsis
Dive into discussions on how to maximize the developability of your pre-clinical cytokine efforts through to the clinic and beyond. Explore the intricacies of preclinical models for cytokine therapeutic development and start early thinking for patient selection and dose profiling. Join this workshop to:
- Navigate what steps can be taken in early development to improve translation and clinical success • Hear learnings from organizations in the clinic to de-risk your pipeline
- Uncover next generation in-vivo and in-vitro models • Assess how to design your IND enabling toxicology study to reduce cost
- Explore patient selection, using predictive biomarkers and predictive modelling for clinical success • Discuss PKPD modelling, predicting the right dose and using dose regimens
- Can preclinical models help with clinical development?