Ionizable Lipid Optimization for LNP-Mediated mRNA Delivery to Enhance Biological Performance
Time: 2:00 pm
day: Conference Day Two
Details:
- Introducing lipid nanoparticles (LNPs) for the delivery of nucleic acids, with a focus on the role of the amino (ionizable) lipid component
- Outlining medicinal chemistry strategies for optimizing lipid/LNP physical properties, pharmacokinetics, and biological performance
- Utilizing computational modelling to guide the design of improved delivery vehicles for mRNA
