Randolph Lopez

Randolph Lopez

Company: A-Alpha Bio

Job title: Co-founder & Chief Technology Officer


Precision Engineering of Cytokine Therapeutics by Measuring Protein Interactions at Scale With AlphaSeq 2:10 pm

Utilizing AlphaSeq, a tool for massive PPI data generation, IFNA2 and IL-21 cytokine variants are engineered with varied affinities for human and mouse receptors, guiding precision development of cancer therapeutics with reduced systemic toxicity Exploring protein affinities and signaling potencies were orthogonally measured using biolayer interferometry and human PBMC phosflow assays, leading to the fusion…Read more

day: Conference Day One

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